Description
Permethrin Cream – Scabies & Lice Treatment
Permethrin Cream is a trusted treatment for scabies and crab lice (pubic lice) infestations. Containing the active ingredient permethrin, this medicated cream works by killing the mites or lice that cause itching, redness, and rashes.
Safe and effective, Permethrin Cream for scabies provides relief with just one application in most cases, making it a fast-acting solution recommended by healthcare professionals.
What is Permethrin Cream?
Permethrin Cream 5% is a topical treatment used to eliminate scabies mites and lice infestations. It is applied directly to the skin and works by paralysing and killing the parasites responsible for symptoms such as itching, rash, and skin irritation.
It should only be applied externally to unbroken skin and should not be used internally.
How Does Permethrin Cream Work?
Permethrin belongs to a class of medicines known as pyrethroids. When applied to the skin, it penetrates the surface and destroys lice and mites by affecting their nervous system.
Once the scabies mites or lice are killed, the associated symptoms – including rash, itching, and irritation – typically clear up.
How to Use Permethrin Cream
Always follow your doctor’s or pharmacist’s advice and carefully read the patient information leaflet before use.
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Apply the cream to clean, dry, cool skin (not after a hot bath).
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Massage a thin layer of cream over the whole body from the neck down.
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For children and elderly patients, also apply to the face, scalp, ears and neck (avoid eyes and mouth).
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Leave the cream on for at least 8 hours (overnight is ideal).
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Wash off thoroughly with soap and water the next morning.
Recommended dosage:
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Adults & children over 12 years: up to 30g (1 full tube).
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Children 6-12 years: up to 15g (half a tube).
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Children 2 months-5 years: up to 7.5g (quarter tube).
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Adults with pubic lice (crab lice): up to 30g, including application to beard or moustache if affected.
Tip: Wash bedding, clothes, and towels used in the 48 hours prior to treatment to prevent reinfestation.
How Effective is Permethrin Cream?
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Clinically proven scabies treatment – usually effective after a single application.
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One treatment is often enough, but occasionally a second may be needed after 7-14 days.
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To prevent reinfection, ensure close contacts and sexual partners are also treated.
Side Effects of Permethrin Cream
Like all medicines, Permethrin Cream can cause side effects, although not everyone will experience them.
Common side effects include:
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Temporary itching or irritation
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Reddening of the skin
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Mild burning, stinging, or tingling sensation
These effects are usually short-lived and improve as the skin heals.
Frequently Asked Questions about Permethrin Cream
How long does it take for Permethrin Cream to work for scabies?
Most people see results after one application left on for 8-12 hours. Itching may persist for a few weeks, but this is often due to the body’s allergic reaction to dead mites, not ongoing infestation.
Can I use Permethrin Cream on my baby?
Children under 2 years should only be treated with Permethrin Cream on the advice of a doctor. For children under 23 months, always seek medical guidance.
Is one treatment enough for scabies or lice?
In most cases, yes. However, if symptoms persist, a second treatment may be required after 7-14 days.
Do I need to treat the whole family?
Yes – anyone in close contact should also be treated to avoid reinfection, even if they don’t show symptoms.
Is Permethrin Cream safe during pregnancy?
Permethrin is generally considered safe in pregnancy and breastfeeding, but always consult your doctor first.
Key Benefits of Permethrin Cream
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Effective scabies treatment with one application
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Kills lice and mites at the source
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Clinically proven and widely recommended by doctors
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Suitable for adults and children (2 months +) under guidance
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Easy-to-use cream for home application
Patient Information Leaflet
Click here to view the Permethrin Cream Patient Information Leaflet.

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