Description
What Is Canesten Thrush Combi – Pessary & External Cream?
Canesten Thrush Combi – Pessary & External Cream is a complete dual-action treatment for vaginal thrush (candida infection).
It combines a pessary (internal tablet) to target the infection at its source and an external cream to soothe itching, soreness, and irritation around the vaginal area.
This trusted Canesten treatment provides comprehensive relief from the symptoms of thrush and helps restore comfort quickly and effectively.
Learn more about thrush and its symptoms on the NHS website.
Canesten Thrush Combi Key Benefits
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Complete two-part treatment: internal pessary + external cream
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Relieves itching, soreness, and discharge caused by thrush
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Treats the infection at the source and soothes external irritation
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Contains clotrimazole, a clinically proven antifungal ingredient
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Convenient single-dose pessary for effective overnight relief
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Suitable for women aged 16-60 years who have been previously diagnosed with thrush
How Canesten Thrush Combi Works
Both the pessary and cream contain clotrimazole, an antifungal medicine from the azole family.
Clotrimazole works by destroying the fungal cell membrane, preventing the Candida albicans yeast from multiplying and causing infection.
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The pessary works internally, dissolving overnight to clear the infection at its source.
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The cream provides external relief, soothing itching and burning while reducing redness.
Together, they provide fast, effective treatment and help prevent the infection from returning.
Who Can Use It / Who Shouldn’t
Suitable for:
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Women aged 16–60 years who have had thrush before
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Those experiencing itching, soreness, or thick white discharge
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Use for single-episode treatment of vaginal thrush
Do not use if:
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You are allergic to clotrimazole or any other ingredients
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You are under 16 or over 60 years old without GP advice
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You have irregular bleeding, sores, or abdominal pain
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You are pregnant or breastfeeding (seek medical advice before use)
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You have recurrent thrush (2+ episodes in 6 months) – consult your GP
How to Use Canesten Thrush Combi
Pessary (Internal Tablet)
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Wash your hands before and after use.
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Remove the pessary from the foil blister pack.
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Use the applicator to insert the pessary high into the vagina, preferably at bedtime.
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Allow it to dissolve overnight while you sleep.
The pessary works best when inserted before lying down, helping ensure full absorption.
External Cream (2% Clotrimazole)
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Apply a thin, even layer of cream to the affected external area.
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Smooth in gently 2-3 times daily until symptoms disappear.
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The cream can also be used by your sexual partner if they experience irritation or soreness.
How Long Does Canesten Combi Take to Work?
Most users experience relief within 1-3 days, with full symptom resolution within 7 days.
If symptoms persist beyond this time or return within a few weeks, consult your doctor or pharmacist.
Canesten Thrush Combi Ingredients
Active ingredient:
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Clotrimazole 500mg pessary
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Clotrimazole 2% w/w external cream
Other ingredients include:
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Calcium lactate pentahydrate
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Lactose monohydrate
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Magnesium stearate
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Polysorbate 80
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Cetostearyl alcohol
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Sorbitan stearate
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Purified water
Free from perfumes and parabens.
Safety Information & Side Effects
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For vaginal use only – do not swallow the pessary.
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Avoid sexual intercourse during treatment.
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Do not use tampons, spermicides, or douches while using this product.
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Some people may experience mild burning, itching, or irritation after application.
Seek medical advice immediately if you notice:
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Rash, swelling, or difficulty breathing (possible allergic reaction)
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Abdominal pain, fever, or abnormal discharge
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Persistent or worsening symptoms after 7 days
Storage Instructions
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Store below 25°C in a dry place.
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Keep out of sight and reach of children.
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Do not use after the expiry date printed on the box.
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Dispose of used packaging safely – do not flush.
Thrush Prevention Tips
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Wear cotton underwear and avoid tight clothing
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Avoid perfumed soaps, wipes, and bath products
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Change out of wet swimwear promptly
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Wipe front to back after using the toilet
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Treat both partners if infections are recurring
Frequently Asked Questions
Can I use Canesten Thrush Combi during my period?
No. It is best to wait until your period has finished, as menstrual flow can reduce treatment effectiveness.
Can I use the cream alone?
The cream only relieves external symptoms. The pessary is needed to treat the infection at its source.
Can Canesten Thrush Combi be used during pregnancy?
Yes, but only under the advice of a GP. The pessary should be inserted without an applicator during pregnancy.
Can my partner use the cream?
Yes, if they have irritation or redness on the penis. This helps prevent reinfection.
How long does Canesten Thrush Combi take to work?
Most women experience relief within 1-3 days, with full recovery in up to 7 days.
Can I have sex while using Canesten Thrush Combi?
No. Avoid intercourse during treatment as the infection may transfer and the product can weaken latex condoms.

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