£49.99
Vydura 75mg Wafers provide fast, effective relief from migraine attacks with or without aura. The easy-to-use, dissolvable wafers offer convenient, quick absorption for rapid symptom control.
Vydura 75mg is an innovative migraine treatment and prevention medicine for adults, containing the active ingredient Rimegepant. It belongs to a class of medicines known as CGRP receptor antagonists (calcitonin gene-related peptide inhibitors).
During a migraine attack, levels of CGRP increase in the brain, contributing to inflammation, blood vessel dilation, and pain. Rimegepant works by blocking CGRP receptors, reducing their activity to help:
Stop active migraine attacks quickly
Prevent future migraine episodes when taken regularly
This dual-action mechanism makes Vydura 75mg one of the most effective migraine solutions currently available.
Vydura can significantly reduce migraine pain within 2 hours of taking a dose. In clinical studies involving over 3,500 adults:
20% of Vydura users reported being pain-free within 2 hours, compared with 12% using a placebo.
It also reduced light sensitivity (photophobia), sound sensitivity (phonophobia), and nausea associated with migraine attacks.
In a 12-week study of 747 adults who experienced frequent migraines:
Participants taking Vydura every other day experienced a reduction of 4.3 migraine days per month, compared to 3.5 days in the placebo group.
This demonstrates its value as both an acute treatment and a preventative therapy for migraine sufferers.
For active migraine attacks:
Take one Vydura 75mg oral lyophilisate (dissolvable tablet) as soon as symptoms begin.
Do not take more than one dose in 24 hours.
For migraine prevention:
Take one tablet every other day to reduce the frequency and severity of migraine attacks.
How to use:
Place the tablet on or under your tongue and allow it to dissolve without water. The mint-flavoured tablet dissolves quickly and can be taken without swallowing whole.
Do not take Vydura if you:
Are allergic to Rimegepant or any of the ingredients listed below.
Have severe liver impairment or severely reduced kidney function (including those on dialysis).
If an allergic reaction occurs – such as rash, swelling, or difficulty breathing – stop using the medicine immediately and seek medical attention. These symptoms may appear several days after taking the dose.
Before using Vydura, consult your doctor or pharmacist if you:
Have moderate liver or kidney problems
Are taking any other CGRP inhibitors or migraine medications
Are pregnant, trying to conceive, or breastfeeding
Vydura does not affect your ability to drive or operate machinery.
Some medicines may alter how Vydura works or increase the risk of side effects. Inform your doctor if you are taking or plan to take:
Antifungal agents: itraconazole, fluconazole
Antiviral drugs: ritonavir
Immunosuppressants: cyclosporin
Heart medicines: diltiazem
Antiepileptics: phenobarbital
Herbal remedies: St John’s Wort
Other: bosentan, modafinil
Like all medicines, Vydura can cause side effects, although not everyone will experience them.
Nausea
Allergic skin reactions (rash, swelling, difficulty breathing)
Stop using Vydura and contact your doctor immediately if you experience signs of a severe allergic reaction.
Each Vydura oral lyophilisate (orodispersible tablet) contains:
Active ingredient: 75 mg Rimegepant
Other ingredients: gelatin, mannitol, sucralose, and mint flavouring
These components help the tablet dissolve quickly on the tongue, allowing for fast absorption and rapid migraine relief.
| Study Type | Participants | Results |
|---|---|---|
| Acute migraine relief | ~3,500 adults | 20% pain-free at 2 hours vs. 12% placebo |
| Symptom relief (light/sound sensitivity) | ~3,500 adults | 36% improved vs. 27% placebo |
| Migraine prevention (12 weeks) | 747 adults | 4.3 fewer migraine days vs. 3.5 placebo |
Most people experience relief within two hours of taking a dose. Some may feel better even sooner.
Yes – Vydura can be safely taken alongside standard pain relief medicines if needed for additional comfort.
For prevention, Vydura should be taken every other day, not daily, unless otherwise advised by your doctor.
No – Vydura is a CGRP receptor antagonist, which works differently from triptans and can be suitable for people who cannot tolerate them.
Consult your doctor before using Vydura if you are pregnant or breastfeeding, as safety data is still limited.
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