Description
What is Sumatriptan?
Key Facts
- Fast-acting triptan for migraines with or without aura
- Take at headache onset; may repeat after 2 hours if needed
- Available strengths: 50 mg and 100 mg
- UK Prescription Only (POM)
How it works
Sumatriptan belongs to a class of medicines known as triptans. It works by narrowing blood vessels in the brain, reducing inflammation, and relieving migraine pain and associated symptoms such as nausea and light/sound sensitivity.
Who can use it
Adults who experience migraines, with or without aura. It should only be used after clinical assessment and prescription.
Dosage & Directions
When to take
Take one tablet at the onset of migraine symptoms. It is not for daily or preventive use.
Redosing
If migraine returns, a second dose may be taken, but only after two hours. Do not exceed the maximum recommended daily dose.
With food or without
Sumatriptan can be taken with or without food, depending on patient preference or clinical advice.
Side Effects
Common
- Flushing or warm sensation (usually mild and temporary)
- Dizziness or drowsiness (may affect ability to drive or operate machinery)
- Fatigue or weakness
Serious — seek help immediately
- Chest pain or tightness
- Shortness of breath
- Severe allergic reactions such as swelling of the face, lips, tongue, or throat
Warnings & Interactions
Cardiovascular Risk
Patients with a history of heart disease, high blood pressure, or stroke should avoid Sumatriptan unless specifically approved by a healthcare provider.
Drug Interactions
Do not combine with ergotamines, other triptans, or certain antidepressants (SSRIs, SNRIs) due to interaction risks.
Driving and Machinery
Sumatriptan may cause drowsiness or dizziness; avoid driving or operating machinery until you know how it affects you.
Ingredients
Active
Each tablet contains either 50 mg or 100 mg of sumatriptan succinate.
Inactive
Includes lactose monohydrate, microcrystalline cellulose, and croscarmellose sodium.
FAQs
- How quickly does Sumatriptan work?
Most patients experience relief within 30–60 minutes.
- Can I take a second tablet the same day?
Yes, at least 2 hours after the first dose. Do not exceed the maximum daily dose.
- Can Sumatriptan prevent migraines?
No. It is only for acute migraine attacks, not prevention.
- Is it safe with antidepressants?
Check with your prescriber. Certain antidepressants (SSRIs, SNRIs) may interact.
Delivery & Repeats
Prescription required in the UK. Medication is dispatched in discreet packaging with guidance for repeat prescriptions.
Storage & Other Information
Store below 25 °C. Keep out of reach of children. Do not exceed the recommended frequency of use.

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