Description
What is Sildenafil 100mg?
Sildenafil 100mg is a prescription-strength treatment for erectile dysfunction (ED). It helps increase blood flow to the penis during sexual stimulation, supporting a firmer, longer-lasting erection. Typical onset is 30–60 minutes, with effects that can last for up to around 4 hours.
Who is it for? Who should avoid it?
Suitable for
Adult men with erectile dysfunction, when prescribed by a clinician and used as directed.
Do not use if
You take nitrates (for chest pain) or riociguat; have been advised to avoid sexual activity due to heart problems; have severe liver disease; certain rare eye conditions; or if your prescriber has advised against it.
How it works
Sildenafil belongs to a group of medicines called PDE5 inhibitors. It relaxes blood vessels in the penis, increasing blood flow during arousal. Sexual stimulation is required for it to work.
Directions & Dosage
When to take
Take one tablet 30–60 minutes before sexual activity with water. Taking it with a heavy or high‑fat meal can delay how quickly it works.
Dose
Usual dose: one 100mg tablet when needed. Maximum: one tablet in 24 hours.
Missed dose
Not applicable for ‘as‑needed’ use. Do not take extra tablets to make up for a missed opportunity.
Ingredients
Active: Sildenafil citrate 100mg (equivalent to 100mg sildenafil).
Excipients: See patient information leaflet/pack for full list.
Side effects
Common side effects include headache, flushing, dizziness, indigestion, and changes in vision (e.g., a blue tinge). These are usually mild and short‑lived.
Seek urgent help
Stop use and seek medical help if you experience chest pain, sudden vision loss, or an erection lasting longer than 4 hours (priapism).
Interactions & warnings
Do not use with nitrates or riociguat. Use caution with alpha‑blockers (risk of low blood pressure). Limit alcohol, as it may reduce effectiveness and increase side effects. Speak to your clinician about other medicines you take.
Available strengths & alternatives
This page is for Sildenafil 100mg. Lower strengths may be suitable depending on your response and tolerability:
- Sildenafil 50mg (link: /sildenafil-50mg-tablets/)
- Sildenafil 25mg (link: /sildenafil-25mg-tablets/)
Explore more options in our Erectile Dysfunction treatments category (link: /prescription-treatments/erectile-dysfunction/).
FAQs
How quickly does Sildenafil 100mg work?
Effects typically begin within 30–60 minutes and may last up to 4 hours.
Can I take Sildenafil with alcohol?
Limit alcohol; it can reduce effectiveness and increase side effects.
Is it safe for daily use?
Sildenafil is taken as needed. Do not exceed one 100mg tablet in 24 hours; speak to a clinician if you need frequent dosing.
How long does it last?
Up to around 4 hours, varying by individual factors such as food and metabolism.
What if 100mg doesn’t work?
Do not exceed the dose. Check timing, food, and interactions; consult your prescriber for alternatives or a different treatment.

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