Side Effects of Anti-Malaria Medications
Travelling to a malaria-risk country? Anti-malarial tablets are an essential part of your travel protection plan. While highly effective at preventing malaria, these medications can have side effects you should be aware of.
At MedCare Health Clinic in Preston, we offer expert travel health consultations to help you choose the best option for your destination and health profile.
Why Side Effects Occur
Anti-malaria tablets work by interfering with the life cycle of the Plasmodium parasite inside your bloodstream or liver. Since these drugs affect biological systems, some people experience temporary side effects. Knowing what to expect allows you to manage symptoms and make informed choices about your travel protection.
Commonly Prescribed Anti-Malaria Medications and Their Side Effects
1. Atovaquone/Proguanil (Malarone)
Common Side Effects:
- Nausea and vomiting
- Stomach pain
- Diarrhoea
- Headache
- Dizziness
- Vivid dreams
Less Common:
- Skin rash
- Mouth ulcers
- Temporary hair loss
Notes: Generally well tolerated. Usually taken once daily starting 1–2 days before travel and for 7 days after return.
2. Doxycycline
Common Side Effects:
- Sun sensitivity (photosensitivity)
- Nausea or acid reflux
- Diarrhoea
- Vaginal thrush in women
Less Common:
- Oesophageal irritation if not swallowed with water
- Allergic skin reactions
Notes: Must be taken with food and plenty of water. Continue daily for 4 weeks after travel.
3. Mefloquine (Lariam)
Common Side Effects:
- Vivid dreams or insomnia
- Dizziness
- Nausea
- Anxiety or mood changes
Serious But Rare:
- Seizures
- Hallucinations
- Depression
Notes: Usually taken weekly. Not suitable for individuals with a history of mental health conditions.
Who Should Avoid Certain Tablets?
- Pregnant women: Doxycycline is not recommended; Mefloquine and Malarone may be considered depending on trimester and destination.
- Children under 12: Doxycycline is unsuitable; alternatives like Malarone (pediatric formulation) are preferred.
- Patients with a history of epilepsy or mental health conditions: Should avoid Mefloquine.
- People with liver or kidney issues: Require careful dosing and monitoring.
Your clinician at MedCare Health Clinic will assess your individual health status, current medications, and travel plans to recommend the most appropriate anti-malarial medication.
Managing Side Effects While Travelling
- Start the tablets before travel to see how your body reacts.
- Take tablets with food and water to minimise stomach issues.
- Use sun protection if taking Doxycycline.
- Keep hydrated to reduce headaches and dizziness.
- Report any serious side effects to a healthcare professional promptly.
Trust MedCare Health Clinic for Expert Travel Health Advice
- Personalised malaria prevention plans
- Private prescriptions for anti-malaria tablets
- NHS-compliant yellow fever and travel vaccines
- Advice on managing side effects abroad
Our experienced clinicians ensure your journey is protected with minimal disruption to your health. We stock a full range of anti-malaria tablets and offer same-day appointments. For local, clinician-led prescribing, book same-day malaria tablets in Preston and get a personalised plan.
Book your travel consultation online today: MedCare Health Clinic – Anti-Malaria