Description
Naproxen 500mg Tablets are a prescription-only non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce inflammation, and lower fever. They are commonly prescribed for arthritis, back pain, muscle injuries, gout, and menstrual pain. Order Naproxen 500mg online in the UK following clinical review by a UK-registered prescriber.
What Is Naproxen 500mg?
Naproxen works by inhibiting cyclooxygenase (COX) enzymes, reducing the production of prostaglandins that cause pain, swelling, and inflammation. The 500mg strength is typically used for moderate to severe inflammatory pain conditions.
What Conditions Is Naproxen 500mg Used For?
Arthritis and Inflammatory Joint Disorders
Relieves pain, stiffness, and swelling in osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
Musculoskeletal and Back Pain
Effective for sprains, strains, tendonitis, and lower back pain.
Gout and Menstrual Pain
Used for acute gout attacks and dysmenorrhoea (painful periods).
Fever and Inflammatory Conditions
Helps reduce fever associated with inflammatory disorders.
Dosage and How to Take
Recommended Dose
Typically one 500mg tablet once or twice daily as directed by your prescriber.
Administration Advice
Swallow whole with water, preferably with food to reduce stomach irritation. Do not exceed prescribed dosage.
Warnings and Precautions
NSAIDs may increase the risk of gastrointestinal bleeding, heart attack, or stroke, particularly with prolonged use. Avoid alcohol. Use caution if taking blood thinners, corticosteroids, or other NSAIDs. Not suitable for patients with active ulcers, severe heart disease, or significant kidney or liver impairment.
Possible Side Effects
Common Effects
Nausea, heartburn, abdominal pain, dizziness, headache, or fluid retention.
Serious Reactions
Seek urgent medical attention for black stools, vomiting blood, severe abdominal pain, chest pain, or signs of allergic reaction.
Ingredients
Active ingredient: Naproxen 500mg.
Refer to the patient information leaflet for full excipient details.
Frequently Asked Questions
- How quickly does Naproxen 500mg work?
Pain relief often begins within 30–60 minutes. - Can I take Naproxen 500mg long-term?
Long-term use should be monitored by a healthcare professional. - Is Naproxen stronger than ibuprofen?
Naproxen generally lasts longer per dose and may provide sustained relief. - Can I combine Naproxen with paracetamol?
Paracetamol may be used alongside if advised by a clinician. - Does Naproxen increase blood pressure?
NSAIDs can increase blood pressure in some individuals. - Can I drink alcohol while taking Naproxen?
Alcohol increases the risk of stomach bleeding and should be avoided. - What happens if I miss a dose?
Take it when remembered unless near the next dose; do not double up. - Can Naproxen cause stomach ulcers?
Yes, especially with long-term or high-dose use. - Is Naproxen safe during pregnancy?
Generally avoided during pregnancy, particularly in the third trimester. - Can Naproxen affect kidney function?
Long-term or high-dose use may impact kidney function. - What are warning signs of serious side effects?
Black stools, vomiting blood, chest pain, or breathing difficulty require urgent medical attention.

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