Description
Lariam (Mefloquine) 250 mg Tablets, available at MedCare Health Clinic, are a trusted antimalarial medicine used for both the prevention and treatment of malaria, including infections caused by chloroquine-resistant Plasmodium falciparum. The active ingredient Mefloquine hydrochloride acts within the red-blood-cell stage of the parasite’s lifecycle, preventing malaria from developing or recurring.
Available Strengths
How Lariam Works
Lariam’s active substance, Mefloquine, targets malaria parasites in their erythrocytic (red-blood-cell) phase, inhibiting their replication and survival. It’s effective against several Plasmodium species, notably P. falciparum and P. vivax, and is recommended by WHO, NHS Fit for Travel, and TravelHealthPro for regions where malaria-parasite resistance is common.
Directions for Use
For Malaria Prevention (Prophylaxis)
- Adults & children > 45 kg: 1 tablet once weekly.
- Start 2–3 weeks before travel to allow blood levels to stabilise.
- Continue weekly while in the malaria area.
- Keep taking for 4 weeks after leaving the risk region.
For Malaria Treatment
- Adults & children > 45 kg: 5 tablets (1250 mg) as a single dose, sometimes divided to limit side effects.
- Always follow your doctor’s prescription and read the Patient Information Leaflet (PIL).
Ingredients
Active Ingredient
- Mefloquine hydrochloride 250 mg
Inactive Ingredients
- Microcrystalline cellulose
- Maize starch
- Poloxamer
- Lactose monohydrate
- Magnesium stearate
Benefits of Lariam 250 mg
- Provides weekly dosing convenience
- Effective against resistant P. falciparum strains
- Dual use – prevention & treatment
- Backed by WHO and NHS travel guidelines
- Ideal for long-term travellers and expats in endemic zones
Possible Side Effects
- Nausea or vomiting
- Dizziness or vertigo
- Headache
- Disturbed sleep (vivid dreams, insomnia)
⚠️ Rare but serious reactions can include mood changes, anxiety, or hallucinations. Stop use and seek immediate medical advice if neuropsychiatric symptoms occur.
Precautions & Warnings
- Not recommended in the first trimester of pregnancy unless no safer alternative is available.
- Inform your doctor if you have a history of depression, anxiety, or seizure disorders.
- Always take Lariam with food and water to reduce stomach upset.
- Continue for 4 weeks post-travel to maintain protection.
Patient Information Leaflet
See the official Lariam 250 mg Patient Information Leaflet (PIL) for full dosing instructions, interactions, and safety advice.
Frequently Asked Questions (FAQs)
When should I start taking Lariam for malaria prevention?
Start 2–3 weeks before travelling to malaria-endemic regions.
How long should I continue after leaving the area?
Continue 1 tablet weekly for 4 weeks after returning home.
What if I miss a dose?
Take it as soon as you remember. If your next dose is due within 24 hours, skip the missed dose – do not double up.
Can Lariam be used during pregnancy?
Not recommended in early pregnancy unless benefits outweigh risks; consult your doctor.
Are there mental-health concerns with Lariam?
Yes – Lariam may trigger neuropsychiatric effects. Avoid if you have a history of mental health conditions.
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