Description
Quick Summary
- Fast-acting triptan for the acute treatment of migraine attacks (with or without aura).
- Relieves migraine pain and can reduce nausea and light/sound sensitivity during an attack.
- Use at the start of a migraine (not for prevention).
- Prescription-only medicine in the UK – supplied after a clinical assessment where offered.
What is Imigran?
Imigran is the branded version of sumatriptan. It belongs to a group of medicines called triptans (5‑HT1B/1D receptor agonists) used to treat migraine attacks. It works by targeting migraine pathways and helping symptoms settle during an active attack.
What Imigran is Used For
- Acute treatment of migraine attacks with or without aura in adults with a migraine diagnosis.
- Not intended for migraine prevention or daily prophylaxis.
How Fast Does Imigran Work?
- Tablets commonly work within about 30–60 minutes for many people (individual response varies).
- Take as soon as the migraine starts for best results (follow your prescriber’s instructions).
Strengths & Dosing (Tablets)
| Strength | Typical start dose (example) | Repeat dose rules (common UK guidance) |
| Imigran 50mg tablets | 1 tablet at migraine onset | If the migraine returns, a second dose may be taken after at least 2 hours if advised. If the first dose had no effect, do not take a second dose for the same attack. |
| Imigran 100mg tablets | 1 tablet at migraine onset (when prescribed) | Same repeat-dose rules. Do not exceed your prescriber’s max daily dose (commonly up to 300mg in 24 hours for tablets). |
How to Take Imigran (Directions)
- Take exactly as prescribed.
- Swallow tablets whole with water.
- Use only when a migraine begins (not every day).
- Do not take a second dose for the same attack if the first dose did not help.
- Avoid medication overuse: frequent use of migraine medicines can worsen headaches -arrange review if you need treatment often.
Who Can Use Imigran? (Eligibility)
- Adults with a confirmed migraine diagnosis where sumatriptan is clinically appropriate.
- A clinician should review your symptoms, cardiovascular risk and current medicines before supply.
Who Should NOT Use Imigran (Contraindications / Exclusions)
- History of heart disease (including coronary artery disease/angina/previous heart attack) or significant circulation problems.
- Previous stroke or TIA.
- Uncontrolled high blood pressure.
- Hemiplegic or basilar migraine (specialist advice required).
- Severe liver disease (unless specifically advised).
- Do not use within 24 hours of ergotamine-containing medicines or another triptan/5‑HT1 agonist.
Interactions (Important)
Tell your prescriber about all medicines and supplements.
- Do not combine with ergotamine or other triptans/5‑HT1 agonists (spacing rules apply).
- Antidepressants such as SSRIs/SNRIs/MAOIs can increase the risk of serotonin syndrome — a clinician should assess this combination.
- St John’s wort can interact with serotonergic medicines – discuss before use.
Side Effects
Common (Often Mild / Short‑Lived)
- Flushing or feeling warm
- Tingling or numbness sensations
- Dizziness or drowsiness
- Fatigue
- Nausea (can also be part of migraine)
Serious – Seek Urgent Medical Help
- Chest pain, tightness or pressure
- Shortness of breath
- Severe allergic reaction (face/lips/throat swelling, wheeze, severe rash)
- Signs of serotonin syndrome (agitation, confusion, fever, sweating, tremor) – especially if on antidepressants
Pregnancy & Breastfeeding
- Use only if a clinician confirms it is appropriate for you.
- If breastfeeding, follow clinician guidance on any recommended time interval after dosing.
Buying Imigran Online in the UK
- Imigran (sumatriptan) is typically supplied as a prescription-only migraine treatment in the UK.
- A regulated online service such as Medcare will require an online consultation/assessment before supply.
- Look for discreet packaging and UK delivery options.
FAQs
Is Imigran for prevention?
No. Imigran treats migraine attacks when they start. It is not a preventive medicine.
What if the headache comes back?
If advised by your prescriber, you can take another dose after at least 2 hours. Do not exceed the maximum daily dose you’ve been prescribed.
Can I take painkillers with Imigran?
Some people use paracetamol or an NSAID alongside a triptan. Check suitability with a clinician/pharmacist, especially if you have stomach, kidney, or bleeding risks.
What if the first dose doesn’t work?
Do not take a second dose for the same attack if the first dose had no effect. Discuss alternatives with a clinician.
When should I seek urgent help?
Seek urgent medical advice for chest pain, severe shortness of breath, severe allergic reaction, or neurological symptoms that are new or unusual for you.

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