Atovaquone & Proguanil 250/100 mg – Malaria Prevention Tablets

Description

Atovaquone and Proguanil 250mg/100mg Tablets, available at MedCare Health Clinic, are a highly effective malaria prevention and treatment medicine. This dual-action medication combines Atovaquone and Proguanil hydrochloride, working together to prevent and treat malaria — especially in areas where parasites have become resistant to chloroquine.

These tablets are suitable for adults and are a trusted choice for travellers visiting malaria-endemic regions in Africa, Asia, and South America.

Available Strengths

• Atovaquone 250mg and Proguanil 100mg Tablets

Directions for Use

For Malaria Prevention (Prophylaxis)

• Take one tablet daily with food or a milky drink.
• Begin 1–2 days before entering a malaria-risk area.
• Continue once daily during travel and for 7 days after leaving the region.

For Malaria Treatment

• Take four tablets once daily for three consecutive days, always with food or a milky drink.
• Follow your doctor’s prescribed dosing schedule carefully for best results.

Ingredients

Active Ingredients

• Atovaquone 250mg
• Proguanil hydrochloride 100mg

Inactive Ingredients

• Microcrystalline cellulose
• Hydroxypropyl cellulose
• Sodium starch glycolate
• Magnesium stearate
• Hypromellose
• Titanium dioxide

How It Works

Atovaquone and Proguanil target the malaria parasite’s lifecycle at different stages:
• Atovaquone blocks the parasite’s energy production inside red blood cells.
• Proguanil interferes with its reproduction in the liver, preventing relapse.

This dual mechanism ensures comprehensive protection and treatment, even against chloroquine-resistant strains of Plasmodium falciparum.

Benefits of Atovaquone and Proguanil

• Effective against chloroquine-resistant malaria
• Suitable for both prevention and treatment
• Convenient once-daily dosing
• Well-tolerated with minimal side effects
• Trusted by UK travel health clinics

Side Effects

• Nausea or vomiting
• Abdominal pain
• Diarrhoea
• Headache

Less common effects: mouth ulcers, skin rashes, or abnormal liver function.

⚠️ If you experience any severe or persistent symptoms, stop use and contact your doctor immediately.

Precautions & Warnings

• Always take tablets with food or milk to improve absorption.
• Not recommended for children under 40 kg unless prescribed.
• Consult your doctor if you have liver or kidney disease.
• Continue protection for 7 days after leaving a malaria region.
• Store below 25°C in a dry place away from sunlight.

Patient Information Leaflet

For full usage instructions, side-effect guidance, and precautions, please refer to the official Atovaquone and Proguanil Patient Information Leaflet (PIL) provided with the medication.

Frequently Asked Questions (FAQs)

When should I start taking Atovaquone and Proguanil for malaria prevention?

Start taking one tablet 1–2 days before entering a malaria-endemic area.

How long should I continue after leaving a malaria area?

Continue for 7 days after leaving to ensure complete parasite clearance.

What if I miss a dose?

Take it as soon as you remember. If it’s close to your next scheduled dose, skip the missed one. Do not double dose.

Should I take it with food?

Yes. Always take with food or a milky drink to improve absorption and reduce stomach upset.